EFSD/JDRF/Lilly European Programme in Type 1 Diabetes Research

2021

Bernd Bodenmiller: University of Zurich - Switzerland
Deep profiling of the human pancreas in early type 1 diabetes stages by highly multiplexed imaging

Lorenzo Piemonti: San Raffaele Center Foundation - Milan, Italy
Exploitation of the immune checkpoints B7-H3 and CD155 to enhance engraftment of hiPSC-derived beta cells

Meritxell Rovira: Bellvitge Biomedical Research Institute (IDIBELL) - Barcelona, Spain
Comprehensive characterisation of human ductal epithelium to identify endogenous progenitors as beta cell source

2020

Carolin Daniel: Helmholtz Zentrum München - Germany
Modelling Islet autoimmunity in humanized MICe to dissect aberrations in immune tolerance (MIMIC)

Mark A. Russell: University of Exeter - United Kingdom
JAKMIP1: Putting the brakes on islet HLA class I hyperexpression in type 1 diabetes?

2019

Francesca D'Addio: University of Milan - Italy
The ATP/P2X7R axis in type 1 diabetes

Patrick Gilon: Catholic University of Louvain - Brussels, Belgium
Mechanisms of impaired glucagon secretion in type 1 diabetes and search for targets to correct them

Benjamin Glaser: Hadassah-Hebrew University Medical Center - Jerusalem, Israel
Drivers and consequences of beta cell senescence in diabetes

Lorenzo Pasquali: IGTP - Badalona, Barcelona, Spain
Deciphering beta cell type 1 diabetes mechanisms and gene targets

Izortze Santin: University of the Basque Country - Leioa - Bizkaia, Spain
Deciphering the role of type 1 diabetes associated lncRNAs in pancreatic beta cell dysfunction

Francesca Spagnoli: King's College London - United Kingdom
Elucidating the mechanisms underlying lineage reprogramming for future diabetes therapies

Nicola Ternette: University of Oxford - United Kingdom
The immune visibility of beta cells as a driver of type 1 diabetes: insights from the HLA peptidome

Sylvaine You: Institut Cochin - Paris, France
Pro-resolving lipid mediators in type 1 diabetes: novel biomarkers and therapeutic targets

2018

Ekaterine Berishvili: University of Geneva - Switzerland
Bioengineering of insulin-secreting, immunoprotective 3D constructs using hydrogel scaffolds

Corrado Maria Cilio: Lund University - Sweden
Unravelling the mechanistic link between enterovirus infection and type 1 diabetes

Nabil Djouder: National Cancer Research Center - Madrid, Spain
Elucidating mechanisms of epigenetic changes in type 1 diabetes and treatment with DNA demethylating drugs

Lilian Mendoza: Imperial College London - UK
Does pregnancy induce changes in Urinary C-peptide Creatinine Ratio in women with type 1 diabetes?

Paolo Monti: Fondazione Centro San Raffaele - Milan, Italy
Generation and characterisation of FOXP3+ regulatory T cells with stem-cell like properties

Noel G. Morgan: University of Exeter - UK
SIRP-alpha, a novel regulator of beta-cell viability

Sjurdur Frodi Olsen: Statens Serum Institut SSI - Copenhagen, Denmark
Impact of maternal diet on offspring risk of type 1 diabetes

Mika Tarvainen: University of Eastern Finland - Kuopio, Finland
The effects of exercise and stress on glucose metabolism in type 1 diabetes (DIAMES project)

Suvi M. Virtanen: National Institute for Health – Haemeenlinna, Finland
Early diet in the development of type 1 diabetes: a prospective birth cohort study

2017

Paul Caton: King's College London - UK
Inhibiting NAMPT to improve beta cell survival and function in type 1 diabetes

Rosa Gasa: IDIBAPS - Barcelona, Spain
Direct reprogramming of human fibroblasts towards insulin-producing cells

Silvia Gregori: San Raffaele Scientific Institute - Milan, Italy
Genetically engineered tolerogenic dendritic cells for antigen-specific immunotherapy for type 1 diabetes

Esteban Nicolas Gurzov: Free University Brussels - Belgium
New markers for pancreatic beta cell imaging in type 1 diabetes

Valeria Sordi: San Raffaele Scientific Institute - Milan, Italy
A role for the intestine in type 1 diabetes autoimmunity

Jorma Toppari: University of Turku - Finland
Molecular basis for aberrant immune response to microbial factors in type 1 diabetes

2016

Mario Galgani: “G Salvatore” National Research Council – Naples, Italy
CD3+CD56+ cells a novel human regulatory population: function and molecular mechanism in type 1 diabetes

Ben Giepmans: University Medical Center Groningen – The Netherlands
Do exocrine – endocrine cell interactions induce inflammatory responses leading to type 1 diabetes?

Agnes Lehuen: Cochin Institute - Paris, France
Role of MAIT cells in type 1 diabetes, studies in patients and mouse models

Christopher O’Callaghan: University of Oxford – UK
Using single-cell transcriptomics to investigate the protective role of Dexi in islet destruction in type 1 diabetes

Carlos Penha-Concalves: Gulbenkian Science Institute – Oeiras, Portugal
Genetic causes of immune-dysregulation in early-onset type 1 diabetes

Romano Regazzi: University of Lausanne – Switzerland
Role of exosome-mediated RNA transfer from immune cells to beta cells in type 1 diabetes development

2015

Yuval Dor: Hebrew University of Jerusalem - Israel
Long-term impact of premature weaning on pancreatic beta cells

Silvia Gregori: Fondazione Centro San Raffaele - Milan, Italy
Negative vaccination strategy for type 1 diabetes based on tolerogenic dendritic cells

Roberto Mallone: Cochin Institute - Paris, France
Oral vaccination with Fc-coupled preproinsulin for type 1 diabetes prevention

Geert Martens: Brussels Free University - Belgium
Combinatorial GAD65/miR-375 profiling to detect immune-mediated beta cell injury in (pre)type 1 diabetes (BetaCell-Probe)

Giuseppe Matarese: CNR - Naples, Italy
Extracellular microRNAs as molecular link between immune and metabolic dysregulation in type 1 diabetes

Nikolay Ninov: Technical University Dresden - Germany
Small molecules and pathways for boosting human beta cell regeneration and survival under inflammation

Rocky Strollo: University Campus Bio-Medico - Rome, Italy
Antibodies to posttranslationally modified insulin as biomarker of type 1 diabetes